Mark K. Greenwald (aa2678)

University information

Title: Associate Department Chair
Unit: Psychiatry
Department: School of Medicine

Contact information

Tolan Park Medical Building, Suite 2A, Room 225
3901 Chrysler Service Drive
Detroit, 48201

Division of Nicotine and Tobacco Research


 Dr. Greenwald’s research focuses on the pharmacological, environmental, and individual difference determinants of drug-seeking behavior including nicotine. Recent work has focused on the effects of stress on nicotine seeking and brain function (Woodcock et al. 2019a, 2019b), and future work is expected to focus on therapeutic approaches including medications and neuromodulation.


Mark K. Greenwald

Psychiatry and Behavioral Neurosciences

Position Title:

Professor and Associate Chair for Research

Office Address:

Tolan Park
Detroit, MI 48201
Suite 2A, Room 225

Office Phone: 313-993-3965

Dr. Greenwald directs the Substance Abuse Research Division, its Human Pharmacology Laboratory and the outpatient treatment research clinic in the Department of Psychiatry and Behavioral Neurosciences at Wayne State University. He previously directed the Ph.D. training program in Translational Neuroscience at the WSU School of Medicine. The National Institute on Drug Abuse (NIDA) has continuously funded his research since 1996. He has been the principal investigator and a co-investigator on many federally funded grants, and regularly reviews manuscripts for many substance abuse related journals and federal grant applications.

Education Training:

Oberlin College, Oberlin, OH, 1983, B.A. (Psychology), Cum laude.1978 - 1983
Oberlin Conservatory of Music, Oberlin, OH, 1983, B.M. (Music Composition)
University of Florida, Gainesville, FL, 1987, M.S. (Clinical & Health Psychology) 1983 - 1992
University of Florida, Gainesville, FL, 1992, Ph.D. (Experimental Psychology)

Postgraduate Training
Research Fellow, Behavioral Pharmacology Research Unit, Dept. of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD. 1994 - 1995
Research Fellow, Addiction Research Center, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD. 1992 - 1994

Research Interests:
  • Substance use disorders
  • Psychopharmacology
  • Determinants of drug use
  • Development of addiction treatments
  • Brain imaging
Clinical/Research Interests:

Substance Abuse

Mark K. Greenwald

Translational Neuroscience Program

Title: Professor and Associate Chair-Research
Research Interests:

Pharmacological, environmental and individual difference determinants of drug-seeking/use behavior (primary endpoint) and neural processes (measured with in vivo imaging methods) related to these behaviors.


Opioid, cocaine, marijuana, nicotine, and alcohol use disorders.




PET (opioid and dopamine), 1H spectroscopy, fMRI and EEG.

Key Collaborators

Leslie Lundahl, David Ledgerwood and Cynthia Arfken (substance use disorders, HIV/AIDS); Jeffrey Stanley (1H spectroscopy); Vaibhav Diwadkar (fMRI, learning/memory); Sylvie Naar-King and Paul Burghardt (stress, physical activity and obesity); Terrance Albrecht, Ann Schwartz and Jennifer Beebe-Dimmer (KCI: chemotherapy-induced peripheral neuropathy); Timothy Roehrs (Henry Ford: EEG, sleep, pain); Margit Burmeister (Univ. of Michigan: pharmacogenetics).

Mark K. Greenwald

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