Sorin Draghici (ad3147)
Ph.D 1995, St. Andrews University
Computational biology, systems biology, data integration, disease subtype discovery, drug repurposing
Intelligent Systems and Bioinformatics Laboratory (ISBL)
Professor of Computer Sciences College of Engineering, and Professor of Obstetrics and Gynecology (Secondary)
Advisor/Mentor. Department of Computer Science PhD Program.
Our research is focused on systems biology applied to human reproduction and is currently supported by one NSF and two NIH grants totaling over 4 million. We use artificial intelligence, machine learning and data mining techniques, applied to high-throughput biological data in order to gain novel insights into complex disease mechanisms.
- Ichchha Madan, Nandor Gabor Than, Roberto Romero, Piya Chaemsaithong, Jezid Miranda, Adi Laurentiu Tarca, Gaurav Bhatti, Sorin Drăghici, Lami Yeo, Moshe Mazor, Sonia S. Hassan, and Tinnakorn Chaiworapongsa. The peripheral whole-blood transcriptome of acute pyelonephritis in human pregnancy. Journal of Perinatal Medicine. 2014 Jan;42(1):31-53. PMID: 24293448.
- Michele Donato, Zhonghui Xu, Alin Tomoiaga, James G. Granneman, Robert G. MacKenzie, Riyue Bao, Nandor Gabor Than, Peter H. Westfall, Roberto Romero, and Sorin Drăghici. Analysis and correction of crosstalk effects in pathway analysis. Genome Research. 2013 Nov;23(11):1885-1893. PMID: 23934932
- Stephen A. Krawetz, Adele Kruger, Claudia Lalancette, Rebecca Tagett, Ester Anton, Sorin Drăghici, and Michael P. Diamond. A survey of small RNAs in human sperm. Human Reproduction. 2011 Dec; 26(12):3401-3412. PMID: 2198909
- Seung Yon Rhee, Valerie Wood, Kara Dolinski, and Sorin Drăghici. Use and misuse of the gene ontology annotations. Nature Reviews Genetics. 2008 Jul;9(7):509-515. Review. PMID: 18475267.
Sorin Drăghici, Purvesh Khatri, Adi Laurentiu Tarca, Kashyap Amin, Arina Done, Călin Voichiţa, Constantin Georgescu, and Roberto Romero. A systems biology approach for pathway level analysis. Genome Research. 2007 Oct;17(10):1537-1545. PMID: 17785539
Return to Search