Donal S. O'Leary Ph.D. (aa3510)

Donal S. O'Leary Ph.D. (aa3510)

University Information

Title: Professor
Unit: Physiology
Department: School of Medicine

Contact Information

4126 Scott Hall
Detroit, 48202

Cardiovascular Research Institute (CVRI)

Title: Professor, Physiology
Office Address: 4126 Scott Hall, 540 E. Canfield, Detroit, MI 48201
Areas of Research:

Neural control of cardiovascular function during exercise in heart failure and hypertension. Role of central adenosine receptors in differential control of sympathetic activity.

Laboratory Web Site:



Office Address: 4126 Scott Hall
Phone: 313-577-9074
Fax: 313-577-5494
Position Title: Professor and Director of Cardiovascular Research
Areas of Interest: Cardiovascular physiology
Narrative Bio:

Donal S. O'Leary, Ph.D., is Professor and Director of Cardiovascular Research in the Department of Physiology. A graduate of Miami University (B.A.) and The University of Texas Health Science Center at San Antonio (Ph.D.), Dr. O'Leary is a cardiovascular physiologist interested in the integrative control of the cardiovascular system at rest and during stress.

Dr. O'Leary's research is funded via the National Institute of Health, Heart, Lung and Blood Institute and is focused on understanding the neural and hormonal mechanisms of control of arterial blood pressure, heart rate, cardiac output,regional blood flow and sympathetic nerve activity during dynamic exercise. His recent findings include determining the relative roles of the arterial baroreflex and the muscle metaboreflex (reflex responses to ischemia of active skeletal muscle) in the control of the cardiovascular system in normal and pathophysiological states such as congestive heart failure. Dr. O'Leary is also currently investigating the role of purinergic mechanisms within the nucleus tractus solaritus in cardio-respiratory homeostasis, regional blood flow and peripheral sympathetic nerve activity. The goals of these studies are to elucidate further the relative roles of cardiovascular reflexes in the control of the cardiovascular system, their interactions, and their mechanisms of action.

Laboratory Web Site: O'Leary Lab



 A complete list of Dr. O'Leary's publications can be found at PubMed-O'Leary

Post Graduate Training:
  • 1986-89 Senior Fellow, Department of Physiology and Biophysics, University of Washington, Seattle, WA
Category Information:

 Neural control of heart rate and blood pressure (effects of exercise, heart failure and hypertension)

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